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    examBoard: Pearson Edexcel
    examType: IGCSE
    lessonTitle: Gas Exchange by Diffusion
    
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Human Gas Exchange » Gas Exchange by Diffusion

What you'll learn this session

Study time: 30 minutes

  • The process of gas exchange by diffusion in humans
  • Structure and function of the lungs and alveoli
  • How oxygen and carbon dioxide are transported in the blood
  • Adaptations of the alveoli for efficient gas exchange
  • Factors affecting the rate of diffusion
  • Common respiratory disorders and their effects on gas exchange

Introduction to Gas Exchange by Diffusion

Every cell in your body needs oxygen to release energy from food and produces carbon dioxide as a waste product. Gas exchange is the process where oxygen from the air enters your bloodstream and carbon dioxide leaves it. This happens in your lungs through a process called diffusion.

Key Definitions:

  • Gas exchange: The process by which oxygen from the air is transferred to the blood and carbon dioxide from the blood is transferred to the air.
  • Diffusion: The movement of particles from an area of higher concentration to an area of lower concentration.
  • Alveoli: Tiny air sacs in the lungs where gas exchange takes place.
  • Ventilation: The movement of air into and out of the lungs (breathing).

💧 The Diffusion Process

Diffusion is a passive process that requires no energy. Gases move from areas of high concentration to areas of low concentration. In the lungs:

  • Oxygen diffuses from the air in the alveoli (high concentration) into the blood (low concentration)
  • Carbon dioxide diffuses from the blood (high concentration) into the air in the alveoli (low concentration)

💪 Why Diffusion Works

Diffusion works effectively for gas exchange because:

  • The concentration gradient is maintained by breathing (bringing in fresh oxygen) and by the body constantly using oxygen and producing carbon dioxide
  • The diffusion distance is very short (the walls of the alveoli and capillaries are extremely thin)
  • There is a large surface area for diffusion to occur (millions of alveoli)

Structure of the Respiratory System

The respiratory system is specially designed to maximise gas exchange. Air enters through your nose or mouth, passes down the trachea (windpipe), through the bronchi and bronchioles and finally reaches the alveoli in the lungs.

The Lungs and Alveoli

Your lungs contain about 300 million alveoli, giving them a total surface area roughly the size of a tennis court! This enormous surface area is crucial for efficient gas exchange.

🌱 Alveolar Structure

Alveoli are tiny balloon-like sacs with very thin walls (just one cell thick). They are surrounded by networks of capillaries, also with walls just one cell thick.

🗺 Surface Area

The lungs contain millions of alveoli, creating a huge surface area for gas exchange - about 70-100 square metres in adults!

💦 Moisture

Alveoli are moist, which helps gases dissolve so they can diffuse across the membranes more easily.

Adaptations for Efficient Gas Exchange

The alveoli have several special features that make them perfect for gas exchange:

🔍 Structural Adaptations

  • Thin walls - just one cell thick, reducing the diffusion distance
  • Moist lining - gases must dissolve to diffuse across membranes
  • Large surface area - millions of alveoli increase the area for diffusion
  • Good blood supply - dense network of capillaries surrounds each alveolus
  • Elastic tissue - allows alveoli to stretch and recoil during breathing

🔬 Functional Adaptations

  • Ventilation - breathing constantly refreshes air in the alveoli
  • Blood flow - continuous circulation maintains concentration gradients
  • Red blood cells - contain haemoglobin that binds with oxygen
  • Surfactant - reduces surface tension, preventing alveoli from collapsing

Gas Transport in the Blood

Once gases have diffused across the alveolar membrane, they need to be transported around the body:

🟢 Oxygen Transport

Oxygen is transported in two ways:

  • Bound to haemoglobin - about 98% of oxygen is carried this way, forming oxyhaemoglobin
  • Dissolved in plasma - only about 2% of oxygen is transported this way

Each haemoglobin molecule can carry four oxygen molecules, making it very efficient.

🟡 Carbon Dioxide Transport

Carbon dioxide is transported in three ways:

  • As bicarbonate ions - about 70% (dissolved in plasma)
  • Bound to haemoglobin - about 23% (forming carbaminohaemoglobin)
  • Dissolved in plasma - about 7%

Case Study Focus: Diving Mammals

Marine mammals like whales and dolphins are excellent examples of adapted gas exchange systems. They can hold their breath for up to 2 hours! This is possible because:

  • They have a much higher concentration of myoglobin (an oxygen-storing protein) in their muscles
  • Their blood can store more oxygen than human blood
  • They can redirect blood flow to vital organs during dives
  • Their metabolism slows down significantly underwater

These adaptations show how gas exchange systems can evolve to suit different environments and lifestyles.

Factors Affecting the Rate of Diffusion

Several factors can speed up or slow down the rate at which gases diffuse across the alveolar membrane:

📈 Concentration Gradient

A larger difference in concentration means faster diffusion. This is why breathing faster during exercise helps - it maintains a high oxygen concentration in the alveoli.

📏 Surface Area

Larger surface area allows more diffusion to occur simultaneously. Damage to the alveoli (as in emphysema) reduces surface area and impairs gas exchange.

📊 Diffusion Distance

Shorter distance means faster diffusion. Conditions that cause thickening of the alveolar walls (like pulmonary fibrosis) slow down gas exchange.

Respiratory Disorders and Gas Exchange

Several conditions can affect the efficiency of gas exchange:

Common Respiratory Disorders

🦠 Asthma

In asthma, the airways become inflamed and narrow, making it harder to breathe. This reduces the amount of air reaching the alveoli, affecting gas exchange. During an asthma attack:

  • Muscles around airways tighten
  • Airways become inflamed and swollen
  • Excess mucus is produced

These changes reduce airflow and impair gas exchange.

🚬 Emphysema

Emphysema is often caused by smoking and involves the destruction of alveolar walls. This:

  • Reduces the surface area for gas exchange
  • Creates larger but fewer air spaces
  • Reduces the elasticity of the lungs

People with emphysema struggle to get enough oxygen into their blood.

Did You Know? The Amazing Numbers of Gas Exchange

Your respiratory system is constantly working at an impressive rate:

  • You breathe about 12-20 times per minute at rest
  • That's around 20,000 breaths per day!
  • Each day, you breathe in about 11,000 litres of air
  • Your lungs extract about 550 litres of oxygen from this air
  • And they remove about 450 litres of carbon dioxide from your blood

All of this happens through the simple process of diffusion - no energy required!

Summary: Gas Exchange by Diffusion

Gas exchange in the lungs is a remarkable example of how structure is perfectly matched to function. The alveoli provide an enormous surface area with very thin walls, allowing oxygen and carbon dioxide to diffuse quickly between the air and blood. This process is passive, requiring no energy input, yet it's essential for all the energy-requiring processes in your body.

Understanding gas exchange helps explain why smoking damages the lungs, why exercise makes you breathe faster and how conditions like asthma affect breathing. It's a perfect example of how physics (diffusion) and biology work together in your body.

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