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Variation and Evolution ยป Variation

What you'll learn this session

Study time: 30 minutes

AQA spec: 4.6.2.1

  • How genes and the environment work together to shape an organism
  • The three causes of variation: genetic, environmental, or both
  • Why all variants come from mutations, and how few of them matter
  • How one rare new phenotype can change a whole species

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Why no two organisms are exactly the same

Look at the people in your class. Nobody looks exactly the same, even brothers and sisters. The same is true of cats, daisies and oak trees. Every population is full of differences.

These differences are what biologists call variation. Understanding where variation comes from is the first step to understanding how species change over time.

Key terms:

  • Variation: the differences in the characteristics of individuals in a population.
  • Genetic causes: differences that come from the genes an organism has inherited.
  • Environmental causes: differences that come from the conditions in which an organism has developed.

How the genome and the environment build the phenotype

An organism's genome is the full set of instructions in its DNA. Those instructions are the starting point. They are not the whole story.

As an organism grows, its genome interacts with its environment. The environment includes things like food, light, temperature, water and the soil it grows in. The result of this interaction is the phenotype, which is the characteristics you can actually observe.

So you can think of it like this:

genome (the instructions) + environment (the conditions) = phenotype (the organism you see)

Two organisms with the same genome can end up with different phenotypes if they grow up in different conditions.

The three causes of variation

Variation may be due to differences in genes, differences in conditions, or a combination of both. Here is how to sort any example.

🧬 Genetic

Caused only by inherited genes. Examples: natural eye colour, blood group, and whether you have free or attached earlobes.

🌾 Environmental

Caused only by the conditions of life. Examples: a scar from a fall, a tree bent by the wind, or a plant grown in the dark being pale.

⚖ Both

Genes set the possibilities and the environment decides the outcome. Examples: height, body mass and skin colour.

Examples of genes and environment together

Height. Genes you inherit from your parents set how tall you could grow. But a person who does not get enough food while growing may not reach that height. Height is caused by genes and the environment.

Plants. Take two cuttings from the same plant. They are clones, so they have identical genes. Grow one on a bright windowsill and one in a dark cupboard. The first is green and sturdy. The second is pale and spindly. The difference between them is environmental.

Skin. The amount of pigment in your skin is controlled by genes, but sunlight makes the skin darker. So skin colour is caused by both.

Worked example

A gardener takes 10 cuttings from one plant, so all 10 are clones with identical genes. Five go in a sunny bed and five go in a shady corner. After 4 weeks, the sunny plants have a mean height of 40 cm and the shady plants have a mean height of 28 cm.
Mean difference = 40 - 28 = 12 cm.
The cuttings have identical genes, so the 12 cm difference is caused by the environment (light).

Genetic variation within a population

In most species there is usually extensive genetic variation within a population. This means that individuals have many different combinations of genes. In sexual reproduction, each offspring gets a mixture of genes, so most individuals are genetically different from each other.

This genetic variation matters because it gives a population many different phenotypes. When conditions change, some individuals may be better suited than others.

All variants come from mutations

Where do the different versions of genes come from in the first place? Every variant arose from a mutation, which is a change to the genome. Mutations occur continuously, all the time, in all living things.

But not every mutation matters. In fact, most do very little. You need to recall these three groups:

😴 Most

Have no effect on the phenotype. The organism looks and works just the same.

🔧 Some

Influence the phenotype. They change a characteristic.

🎯 Very few

Determine the phenotype. They decide the characteristic completely.

The molecular detail of how a mutation changes a protein belongs to the lesson on Protein Synthesis and Mutations. Here, you only need to know how often each type of effect happens.

A rare new phenotype can change a species

Very rarely, a mutation leads to a new phenotype. Sometimes the environment changes, for example the climate becomes cooler or a new disease appears.

If a new phenotype happens to be suited to the environmental change, it can lead to a relatively rapid change in the species.

How this process works step by step is the subject of the next lesson, Evolution by Natural Selection. For now, remember the chain:

  • Mutations occur continuously.
  • Very rarely, one gives a new phenotype.
  • If it suits an environmental change, the species can change quite quickly.

Common mistakes

1. Saying "all variation is genetic". Many differences are caused by the environment, or by both.
2. Saying "all mutations are harmful". Most have no effect, and a few are useful.
3. Saying a mutation "determines" the phenotype in every case. Only very few mutations do that.
4. Mixing up genome and phenotype. The genome is the instructions. The phenotype is what you can observe.

Exam-style question

Two cuttings (clones) were taken from the same parent plant, so they have identical genes. Cutting A was grown in good light. Cutting B was grown in a dark cupboard. After two weeks, A was green and B was pale and tall and thin.

(a) Give the cause of the difference between A and B. [1 mark]

(b) Explain why the cuttings could end up with different phenotypes even though their genomes are the same. [2 marks]

(c) State what proportion of mutations have no effect on the phenotype. Choose from: most, some, very few. [1 mark]

Model answer

(a) The environment (the amount of light they received). (1)
(b) The phenotype is controlled by the genome (1) and its interaction with the environment (1).
(c) Most. (1)

Exam tip

When the question says "same genes", "identical twins" or "clones", the cause of any difference is the environment. Use the key words "genome" and "interaction with the environment" in your answer.

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